Biochemistry of Lipids 3(3-0)

Mid-term, syllabus of Biochem-507: Introduction, classification
and functions of lipids; Classification, structures, physical and chemical
properties of fatty acids; Triglycerides, phospholipids, glycolipids,
sphingoglycolipids, sulpholipids and gangliosides; Lipids as signals, cofactors
and pigments; Structure and physiological significance of cholesterol and its
esters, bile acids and bile salts; Prostaglandins, thromboxanes and leukotriene
and their role in the biological system; Essential oils: composition and
bioactivities;

   

…. PLUS…. First 150 MCQs from chapters 4 of the book ” MCQs in Biochemistry”. MCQs from the taught concepts and book chapters will also appear in the exam.

Final exam, syllabus of Biochem-507:  Lipoprotein system, lipid monolayers, bilayers and micelles; Composition and architecture of biological membranes; Biosynthesis and degradation of triglycerides, saturated and unsaturated fatty acids, phospholipids and cholesterol; Regulation of lipid metabolism; Inborn errors of lipid metabolism; Biosynthesis and utilization of ketone bodies: Lipidation in cell signaling and diseases: functions and therapeutic opportunities; Lipidomics. . 

…. PLUS…. First 200 MCQs from chapters  4 of the book ” MCQs in Biochemistry”. MCQs from the taught concepts and book chapters will also appear in exam. Mid term syllabus will be included in final exam.

…. PLUS…. 30% of final paper will contain syllabus of mid

Assignments and presentations: 

  1. The weightage of the assignment and presentation will be decided later. 
  2. Start preparing your presentations and assignments.
  3. The presentations will also be started right after the mid-term exam.
  4. PPT file should not contain any designing/colours other than figures and diagrams.
  5. Slides should be in 16X9 ratio.
  6. Fonts of all header should be same and of all other text should be same. 
  7. For detailed guidelines about the presentation of research article, visit: https://www.lifesciencesorg.combiochem-720/
  8. Download the template ppt file to make your presentation. The link is here (copy this link and paste in a new tab).
  9. Strictly follow the ppt format and it is better if you write and paste your material in the same ppt file.

K. General Question to be asked during presentation

  1. 1) Pathway or importance of gene/technology/discovery
  2. 2) Rationale
  3. 3) Conclusion of the full article
  4. 4) Conclusion of every figure
  5. 5) New findings presented in the article
  6. 6) Applications of the findings
  7. 7) Future prospective
  8. 8) Applications of the work
  9. 9) Principle of every technique used in the research article

Moreover, provide me a printed summary of your article containing the above headings given under ‘K’.

L. During Presentations, for EVERY FIGURE and graph, we may ask:

1. The Principle of the experiment.
2. The Reason for doing the experiment.
3. The Physiological importance of the figure.
4. The Conclusions of the figure
5. Prepare well objectively and subjectively

NO EXCUSE WILL BE ACCEPTED

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Link to download the book ( MCQs in Biochemistry) is given below:

https://b-ok.cc/dl/1055171/2292c5


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Microsoft Teams meeting
Join on your computer, mobile app or room device

Click here to join the meeting

Meeting ID: 336 479 908 561
Passcode: aH9EDN

_______________________________________________________________

Microsoft teams will be used whenever online classes will be held. You must make your teams name as follows. 

2017-ag-9382 Haidar Iftikhar

2017-ag-10077 Ahmad Faraz

  1. BIOCHEM-507   BIOCHEMISTRY OF LIPIDS       3(3-0)

Course Learning Outcomes

By the end of this course students will be able to;

  1. 1.       Demonstrate an in-depth knowledge of the occurrence, classification and chemical structure of lipids.
  2. 2.       Describe physico-chemical properties and biological importance of lipids.
  3. 3.       Illustrate the basic concepts of metabolism and regulation of lipids.
  4. 4.       Explain biosynthesis and the degradative pathways of fatty acids and lipids.

 

Course Contents

 Theory

Introduction, classification and functions of lipids; Classification, structures, physical and chemical properties of fatty acids; Triglycerides, phospholipids, glycolipids, sphingoglycolipids, sulpholipids and gangliosides; Lipids as signals, cofactors and pigments; Structure and physiological significance of cholesterol and its esters, bile acids and bile salts; Prostaglandins, thromboxanes and leukotriene and their role in the biological system; Essential oils: composition and bioactivities; Lipoprotein system, lipid monolayers, bilayers and micelles; Composition and architecture of biological membranes; Biosynthesis and degradation of triglycerides, saturated and unsaturated fatty acids, phospholipids and cholesterol; Regulation of lipid metabolism; Inborn errors of lipid metabolism; Biosynthesis and utilization of ketone bodies: Lipidation in cell signaling and diseases: functions and therapeutic opportunities; Lipidomics.

Suggested Readings

  1. 1. Abali, E.E., S.D. Cline, D.S. Franklin, S.M. Viselli and D.R. Ferrier. 2021. Biochemistry: Lippincott’s Illustrated Reviews. 8th Ed. Wolters Kluwer Publishing Company, Netherland.
  2. 2. Chatterjea, M.N. and R. Shinde. 2014. Textbook of Medical Biochemistry. 8th Ed. Jaypee Brothers, Medical Publishers (P) Ltd, New Delhi, India.
  3. 3. Nelson, D.L and M.M. Cox. 2021. Lehninger’s Principles of Biochemistry. 8th Ed. WH Freeman and Company, New York, USA.
  4. 4. Rodwell, V., D. Bender, K. Botham, P. Kennelly and P.A. Weil. 2018. Harper’s Illustrated Biochemistry. 31st Ed McGraw-Hill Education / Medical. New York, USA.
  5. 5. Voet, D., J.G. Voet and C.W. Pratt. 2016. Fundamentals of Biochemistry, Life at the Molecular Level. 5th Ed. John Wiley & Sons. Inc. New York, USA. 
Biochem-507, BS  Zool-6 M-Spring 2024, Dr. Muhammad Ali (Assignment of making PPT according to template, link is here)
Sr. Ag No. Student’s Name Assignment
1 2021-ag-9138 AFAF RAMZAN Emodin attenuates high lipid-induced liver metastasis through the AKT and ERK pathways in vitro in breast cancer cells and in a mouse xenograft model
2 2021-ag-9139 AHSAN IQBAL
3 2021-ag-9142 AMINA MUSTAFA
4 2021-ag-9145 AQSA NOREEN
5 2021-ag-9149 FARHA AZIN KHALID
6 2021-ag-9150 FIZZA MAQSOO GILL PRMT6 Regulates RAS/RAF Binding and MEK/ERKMediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation
7 2021-ag-9152 GULSHAN MUKHTAR
8 2021-ag-9153 HADIQA ANWAR
9 2021-ag-9154 HAFIIZ MAHAD IQBAL
10 2021-ag-9155 HAFIZA RUBAB ALI
11 2021-ag-9156 HAFIZA SYEDA MAHIN FATIMA Impaired LXRa Phosphorylation Attenuates Progression of Fatty Liver Disease
12 2021-ag-9157 HIRA SATTAR
13 2021-ag-9158 IQRA MUKHTAR
14 2021-ag-9159 IQRA SHEHZADI
15 2021-ag-9160 MAHNOOR SAEED
16 2021-ag-9161 MALAIKA SHAHBAZ Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis
17 2021-ag-9162 MALAIKA TANVEER
18 2021-ag-9165 MINAHIL SAEED
19 2021-ag-9166 MISHAAL ALI
20 2021-ag-9167 MOMINA NADEEM
21 2021-ag-9168 MUHAMMAD FAISAL Treatment of acromegaly by rosiglitazone via upregulating 15-PGDH in both pituitary adenoma and liver
22 2021-ag-9169 MUHAMMAD TALHA SHAHID
23 2021-ag-9170 MUHAMMAD TARIQ DOGAR
24 2021-ag-9171 MUHAMMAD USMAN SARWAR
25 2021-ag-9172 MUNEEZA QAMAR
26 2021-ag-9173 NADIA AHSAN In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target
27 2021-ag-9174 NIMRA AFZAL
28 2021-ag-9176 QURRAT UL AIN
29 2021-ag-9177 RABIA HANEEF
30 2021-ag-9178 SAIMA ALTAF
31 2021-ag-9180 SARA FATIMA Selective Surface PEGylation of UiO-66 Nanoparticles for Enhanced Stability, Cell Uptake, and pH-Responsive Drug Delivery
32 2021-ag-9181 SEERAT BABAR
33 2021-ag-9182 SEHAR NASIR
34 2021-ag-9184 SHEEZA MUMTAZ
35 2021-ag-9185 SHUMAYL TAJAMMUL
36 2021-ag-9186 SIDRA HAMEED Preventing Allograft Rejection by Targeting Immune Metabolism
37 2021-ag-9188 SUFYAN AHMAD
38 2021-ag-9190 UMAR HASEEB
39 2021-ag-9191 WARDA SHAFIQUE
40 2021-ag-9192 ZAHEER ABBAS
41 2021-ag-9193 ZAHWA NOOR Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-a-Dependent Intensification of Oxidative Stress and Tumor Cell Death
42 2021-ag-9195 ZUNAIRA KANWAL
43    
44    
45    
46     Controlling cancer-induced inflammation with a nucleic acid scavenger prevents lung metastasis in murine models of breast cancer
47    
48    
49    
50    

link is here

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