Biochem-505 (Mid-term syllabus) 3(3-0):
Ch-7 of Lehninger: Carbohydrates: Classification, structures and functions of monosaccharides and oligosaccharides; Hemiacetal and hemiketal structures; Fisher and Howarth projections; Configuration and conformation, boat and chair forms, sugar acids, amino sugars and their derivatives, sialic acids; Biomedical importance of the different carbohydrates; Homopolysaccharides; Starch and glycogen ultrastructure and solution behaviour; Ultrastructure of celluloses, hemicelluloses, gums and pectic substances; Heteropolysaccharides and glycosaminoglycans; Structure, occurrence and functions of hyaluronic acid, heparin, chondriotin sulphates; keratan sulphates and dermatan sulphates. Glycobiology: Structure and functions of glycoconjugates; Current trends and research in the field of glycobiology;
PLUS………. First 200 MCQs from chapter 2 of the book ” MCQs in Biochemistry”.
Biochem-505 (After mid-term exam):
Chapters 14, 15, and 16 of Lehninger: Blood group polysaccharides and their role in blood grouping; Metabolism of carbohydrates; detailed discussion on glycolysis and its feeder pathways, Krebs cycle, glyoxylate cycle, pentose phosphate cycle and glucuronic acid pathway; Gluconeogenesis and glycogen metabolism; Regulation of carbohydrate metabolism; Inborn errors of carbohydrate.
PLUS………. All MCQs from chapter 2 of the book ” MCQs in Biochemistry”.
Biochem-505: Start preparing your presentations and assignments….. Presentations and Assignment will be taken in first class right after mid-term exam. The presentations will also be started right after mid-term exam.
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Assignments and presentations:
- The weightage of the assignment and presentation will be decided later.
- Start preparing your presentations and assignments.
- The presentations will also be started right after the mid-term exam.
- PPT file should not contain any designing/colours other than figures and diagrams.
- Slides should be in 16X9 ratio.
- Fonts of all header should be same and of all other text should be same.
- For detailed guidelines about the presentation of research article, visit: https://www.lifesciencesorg.combiochem-720/
- Download the template ppt file to make your presentation. The link is here (copy this link and paste in a new tab).
- Strictly follow the ppt format and it is better if you write and paste your material in the same ppt file.
K. General Question to be asked during presentation
- 1) Pathway or importance of gene/technology/discovery
- 2) Rationale
- 3) Conclusion of the full article
- 4) Conclusion of every figure
- 5) New findings presented in the article
- 6) Applications of the findings
- 7) Future prospective
- 8) Applications of the work
- 9) Principle of every technique used in the research article
Moreover, provide me a printed summary of your article containing the above headings given under ‘K’.
L. During Presentations, for EVERY FIGURE and graph, we may ask:
1. The Principle of the experiment.
2. The Reason for doing the experiment.
3. The Physiological importance of the figure.
4. The Conclusions of the figure
5. Prepare well objectively and subjectively
NO EXCUSE WILL BE ACCEPTED
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MCQs will appear from text-book and from chapter 2 of the book ” MCQs in Biochemistry”.
Link to download this book is given below:
https://b-ok.cc/dl/1055171/2292c5
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Meeting ID: 316 824 288 013
Passcode: WNyjeA
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Microsoft teams will be used whenever online classes will be held. You must make your first name as your registration number.
2017-ag-9382 Haidar Iftikhar
2017-ag-10077 Ahmad Farazesentaino
Link to download the book ( MCQs in Biochemistry) is here.
BIOCHEM-505 BIOCHEMISTRY OF CARBOHYDRATES 3(3-0)
Theory
Carbohydrates: Classification, structures and functions of monosaccharides and oligosaccharides; Hemiacetal and hemiketal structures; Fisher and Howarth projections; Configuration and conformation, boat and chair forms, sugar acids, amino sugars and their derivatives, sialic acids; Biomedical importance of the different carbohydrates; Homopolysaccharides; Starch and glycogen ultrastructure and solution behaviour; Ultrastructure of celluloses, hemicelluloses, gums and pectic substances; Heteropolysaccharides and glycosaminoglycans; Structure, occurrence and functions of hyaluronic acid, heparin, chondriotin sulphates; keratan sulphates and dermatan sulphates. Glycobiology: Structure and functions of glycoconjugates; Current trends and research in the field of glycobiology; Blood group polysaccharides and their role in blood grouping; Metabolism of carbohydrates; detailed discussion on glycolysis and its feeder pathways, Krebs cycle, glyoxylate cycle, pentose phosphate cycle and glucuronic acid pathway; Gluconeogenesis and glycogen metabolism; Regulation of carbohydrate metabolism; Inborn errors of carbohydrate.
Suggested Readings
- Nelson, D.L and M.M. Cox. 2017. Lehninger Principles of Biochemistry. 7th ed. Worth Publishers, New York.
- Murray, R., D. Bender,M. Botham, P.J. Kennelly,V. Rodwell and P.A. Weil. 2015. Harper’s Illustrated Biochemistry, 30th edition. The McGraw-Hill companies Inc. USA. ISBN-10: 0071825347
- Ferrier, D. R. 2017. Biochemistry: Lippincott’s Illustrated Reviews. 7th Lippincott Williams and Wilkins. U.S.A.
- Chatterjea, M. N. and R. Shinde. 2012. Textbook of Medical Biochemistry. 8th ed (Indian edition). Jaypee Brothers, Medical Publishers (P) Ltd, New Delhi, India
- Voet, D., Voet, J.G and C.W. Pratt. 2013. Fundamentals of Biochemistry, Life at the Molecular Level. 4th John Wiley & Sons. Inc. New York, NY, USA.
Biochem-505, BS Biochem, 5TH, M-Winter 2023, Dr. Muhammad Ali; 28-08-2023 | ||||
Sr. | Ag No. | Student’s Name | Group | Research article for presentation and 1 page summary |
1 | 2021-ag-8431 | Eisha Zahid | G1 | Emodin attenuates high lipid-induced liver metastasis through the AKT and ERK pathways in vitro in breast cancer cells and in a mouse xenograft model |
2 | 2021-ag-8441 | Linta Shafique | ||
3 | 2021-ag-8452 | Muhammad Haris | ||
4 | 2021-ag-8458 | Muhammad Ramzan | ||
5 | 2021-ag-8463 | Nimra Shoukat | ||
6 | 2021-ag-8466 | Noor-Ul-Ain | G2 | PRMT6 Regulates RAS/RAF Binding and MEK/ERKMediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation |
7 | 2021-ag-8472 | Saliha Nawaz | ||
8 | 2021-ag-8484 | Abdul Qadeer | ||
9 | 2021-ag-8485 | Aleena Khalid | ||
10 | 2021-ag-8486 | Aleeza Tahir | ||
11 | 2021-ag-8487 | Ali Raza | G3 | Impaired LXRa Phosphorylation Attenuates Progression of Fatty Liver Disease |
12 | 2021-ag-8488 | Amna Hamid | ||
13 | 2021-ag-8490 | Anooma | ||
14 | 2021-ag-8491 | Ansa Sehar | ||
15 | 2021-ag-8492 | Areej Fatima Ikram | ||
16 | 2021-ag-8493 | Asnan Saleem | G4 | Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis |
17 | 2021-ag-8494 | Ayesha Hassan | ||
18 | 2021-ag-8495 | Ayesha Tahir | ||
19 | 2021-ag-8496 | Esha Batool | ||
20 | 2021-ag-8497 | Esha Mujahid | ||
21 | 2021-ag-8498 | Fatima Haider | G5 | Treatment of acromegaly by rosiglitazone via upregulating 15-PGDH in both pituitary adenoma and liver |
22 | 2021-ag-8499 | Fatima Tahir | ||
23 | 2021-ag-8500 | Ghazia Ashraf | ||
24 | 2021-ag-8501 | Hadia Akram | ||
25 | 2021-ag-8502 | Hafsa Areej | ||
26 | 2021-ag-8503 | Iman Fatima | G6 | In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target |
27 | 2021-ag-8504 | Iman Fatima | ||
28 | 2021-ag-8505 | Iqra Javed | ||
29 | 2021-ag-8507 | Kashaf E Noor | ||
30 | 2021-ag-8509 | Khadija Fatima | ||
31 | 2021-ag-8510 | Kiran Arshad | G7 | Selective Surface PEGylation of UiO-66 Nanoparticles for Enhanced Stability, Cell Uptake, and pH-Responsive Drug Delivery |
32 | 2021-ag-8511 | Mahnoor | ||
33 | 2021-ag-8512 | Mahnoor Fatima | ||
34 | 2021-ag-8513 | Manahil Kashif | ||
35 | 2021-ag-8514 | Maryam Naseer | ||
36 | 2021-ag-8515 | Minahil | G8 | Preventing Allograft Rejection by Targeting Immune Metabolism |
37 | 2021-ag-8517 | M.Ahtesham Muhedeen | ||
38 | 2021-ag-8518 | M. Ehtisham Basel | ||
39 | 2021-ag-8521 | Muhammad Shahzad | ||
40 | 2021-ag-8525 | Muqaddas Raza | ||
41 | 2021-ag-8526 | Naila Nawaz | G9 | Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-a-Dependent Intensification of Oxidative Stress and Tumor Cell Death |
42 | 2021-ag-8527 | Namal Rauf | ||
43 | 2021-ag-8528 | Nimra Akram | ||
44 | 2021-ag-8529 | Noor Fatima | ||
45 | 2021-ag-8530 | Noor Fatima | ||
46 | 2021-ag-8531 | Noreen Ayesha | G10 | Controlling cancer-induced inflammation with a nucleic acid scavenger prevents lung metastasis in murine models of breast cancer |
47 | 2021-ag-8532 | Rafia Zulfiqar | ||
48 | 2021-ag-8533 | Sadaqat Ali | ||
49 | 2021-ag-8535 | Toima Riaz | ||
50 |
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